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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R2
All Species:
15.45
Human Site:
S73
Identified Species:
37.78
UniProt:
Q13319
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13319
NP_003927.1
367
38705
S73
W
K
R
L
V
A
A
S
A
K
K
K
K
G
S
Chimpanzee
Pan troglodytes
XP_516099
367
38658
S73
W
K
R
L
V
A
A
S
A
K
K
K
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
I46
K
N
L
K
R
H
S
I
I
S
V
L
P
W
K
Dog
Lupus familis
XP_853120
458
47635
S161
W
K
R
L
V
A
A
S
A
K
K
K
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
S73
W
K
R
L
V
A
A
S
A
K
K
K
K
G
S
Rat
Rattus norvegicus
P61810
307
34013
I46
K
N
L
K
R
H
S
I
I
S
V
L
P
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089375
320
35634
T59
S
V
L
I
S
A
L
T
W
K
R
L
V
A
A
Zebra Danio
Brachydanio rerio
NP_001017569
308
34577
R46
I
S
A
L
T
W
K
R
L
V
A
A
S
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
R64
Q
G
W
N
W
S
K
R
N
I
Q
P
V
M
S
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
V75
L
G
L
K
M
F
S
V
S
K
K
K
T
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
49.5
77.2
N.A.
94.3
48.7
N.A.
N.A.
N.A.
58.3
55.5
N.A.
N.A.
N.A.
31.6
36.5
Protein Similarity:
100
99.7
59.1
77.7
N.A.
94.8
58.5
N.A.
N.A.
N.A.
64.5
64.8
N.A.
N.A.
N.A.
42.5
49.8
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
N.A.
N.A.
40
6.6
N.A.
N.A.
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
50
40
0
40
0
10
10
0
20
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
0
0
0
0
0
0
0
0
0
40
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
20
20
10
0
0
0
0
0
% I
% Lys:
20
40
0
30
0
0
20
0
0
60
50
50
40
0
30
% K
% Leu:
10
0
40
50
0
0
10
0
10
0
0
30
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
20
0
10
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
20
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
40
0
20
0
0
20
0
0
10
0
0
0
0
% R
% Ser:
10
10
0
0
10
10
30
40
10
20
0
0
10
10
60
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
10
0
0
40
0
0
10
0
10
20
0
20
0
0
% V
% Trp:
40
0
10
0
10
10
0
0
10
0
0
0
0
20
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _